Photo of Nakamura, Toru M.

Toru M. Nakamura, PhD

Professor

Biochemistry and Molecular Genetics

Pronouns: He/Him/His

Contact

Building & Room:

MBRB Room 2202

Address:

900 South Ashland Ave.

Office Phone:

(312) 996-1988

Email:

nakamut@uic.edu

Related Sites:

Selected Publications

Mennie, A.K., Moser, B.A., Hoyle, A., Low, R.S., Tanaka, K. and Nakamura, T.M. (2019) Tpz1TPP1  prevents telomerase activation and protects telomeres by modulating the Stn1-Ten1 complex in fission yeast. Commun. Biol. 2:297.

Mennie, A.K., Moser, B.A. and Nakamura, T.M. (2018) LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast. Nature Commun. 9(1): 586.

Nie, M., Moser, B.A., Nakamura, T.M. and Boddy, M.N. (2017) SUMO-targeted ubiquitin ligase activity can either suppress or promote genome instability, depending on the nature of the DNA lesion. PLoS Genet. 13(5): e1006776.

Gadaleta, M.C., Das, M.M., Tanizawa, H., Chang, Y.-T., Noma, K.I., Nakamura, T.M. and Noguchi, E. (2016) Swi1Timeless prevents repeat instability at fission yeast telomeres. PLoS Genet. 12(3): e1005943.

Moser, B.A., Raguimova, O.N. and Nakamura, T.M. (2015) Ccq1-Tpz1TPP1 interaction facilitates telomerase and SHREC association with telomeres in fission yeast. Mol. Biol. Cell 26(21): 3857-3866.

Harland, J.L., Chang, Y.-T., Moser, B.A. and Nakamura, T.M. (2014) Tpz1-Ccq1 and Tpz1-Poz1 interactions within fission yeast shelterin modulate Ccq1 Thr93 phosphorylation and telomerase recruitment. PLoS Genet. 10(10): e1004708.

Miyagawa, K., Low, R.S., Santosa, V., Tsuji, H., Moser, B.A., Fujisawa, S., Harland, J.L., Raguimova, O.N., Go, A., Ueno, M., Matsuyama, A., Yoshida, M., Nakamura, T.M. and Tanaka, K. (2014) SUMOylation regulates telomere length by targeting Tpz1TPP1 to modulate shelterin-Stn1 interaction in fission yeast. Proc. Natl. Acad. Sci. U.S.A. 111(16): 5950-5955.

Chang, Y.-T., Moser, B.A. and Nakamura, T.M. (2013) Fission yeast shelterin regulates DNA polymerases and Rad3ATR kinase to limit telomere extension. PLoS Genet. 9(11): e1003936.

Moser, B.A., Chang, Y.-T., Kosti, J. and Nakamura, T.M. (2011) Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast. Nature Struct. Mol. Biol. 18: 1408-1413.

Carneiro, T., Khair, L., Reis, C.C., Borges, V., Moser, B.A., Nakamura, T.M. and Ferreira, M.G. (2010) Telomeres avoid end detection by severing the checkpoint signal transduction pathway. Nature 467(7312): 228-232.